Hypertension
KBI has a cohort of monkeys with spontaneous hypertension identified by the measurement of blood pressure (BP) with High Definition Oscillometry (HDO). Through the screening of a large cohort of monkeys, KBI has established the normal range of BP an
Diabetic Retinopathy
Diabetic retinopathy (DR) is a common complication of diabetes due to abnormalities in retinal blood vessels. Initially, the retinal vessel changes are non-proliferative, thus termed as non-proliferative DR (NPDR). As NPDR progresses, the micro-vess
Diabetic Nephropathy and Chronic Kidney Disease Models
Chronic kidney disease (CKD) including diabetic nephropathy (DN) occurs in approximately 20-40% of the type 2 diabetes (T2D) global population. At KBI, our cynomolgus monkey models of CKD and DN closely resemble all the characteristics of these dise
Obesity and Metabolic Syndrome
KBI has a large colony of obese NHP models readily available for the needs of research services. We routinely evaluate anti-obese efficacy with a wide range of tools including the following techniques:· measurements of caloric intake and body mass
Anatomical Pathology
The KBI Section of Anatomic Pathology offers a full range of diagnostic services. Our state-of-the-art technology and sophisticated modalities are available for the critical and accurate assessments of pathology endpoints that are necessary to suppo
Animal Facilities and Capacity
KBI has the state-of-the-art facilities for breeding, housing and research fully compliant with AAALAC and international standards for 8,000 monkeys. The in-door facilities include an SPF barrier unit, a quarantine building, an animal hospital, a nu